TEL
03-5712121 ext 56501
Student Affairs
吳淑褓 Shu-Pao Wu
Professor
Tel | 03-5712121 #56506
FAX | 03-5723764
Office | TKB R512
Email | spwu@nycu.edu.tw
Lab Tel | 03-5712121 #56559
Education
1999-2004 Ph.D. Chemistry, The Ohio State University, Columbus, OH, USA, Adviser: Professor James A. Cowan
1994-1996 M.S. Chemistry, National Taiwan Normal University, Taipei, Taiwan
1989-1994 B.S. Chemistry, National Taiwan Normal University, Taipei, Taiwan
Experiences
2021/02-now Professor, Applied Chemistry, National Yang Ming Chiao Tung University
2021/02-2023/07 Chairman, Applied Chemistry,National Yang Ming Chiao Tung University
2020/08-2021/01 Chairman, Applied Chemistry, National Chiao Tung University
2015-2021 Professor, Applied Chemistry, National Chiao Tung University
2011-2015 Associate Professor, Applied Chemistry, National Chiao Tung University
2006-2011 Assistant Professor, Applied Chemistry, National Chiao Tung University
2004-2006 Postdoctoral Research Fellow, University of California, Berkeley, CA. Adviser: Professor Judith P. Klinman
Honors
2011 The outstanding research award for young scholar, the college of science, National Chiao Tung University, Taiwan.
Academic achievements
Journal articles
- Sanay Naha, Shu-Pao Wu*, Sivan Velmathi*, Naphthalimide based smart sensor for CN−/Fe3+ and H2S. Synthesis and application in RAW264.7 cells and zebrafish imaging, RSC Advance, 2020, 10, 8751-8759.
- Pham Quoc Nhien, Wei-Lun Chou, Tu Thi Kim Cuc, Trang Manh Khang, Chia-Hua Wu, Chia-Hua Wu, Natesan Thirumalaivasan, Bui Thi Buu Hue, Judy I. Wu, Shu-Pao Wu, Hong-Cheu Lin*, Multi-Stimuli Responsive FRET Processes of Bifluorophoric AIEgens in an Amphiphilic Copolymer and Its Application to Cyanide Detection in Aqueous Media, ACS Appl. Mater. Interfaces 2020, 12, 9, 10959-10972
- Decibel P. Elpa, Shu-Pao Wu*, Pawel L. Urban*, Rapid Extraction and Analysis of Volatile Solutes with an Effervescent Tablet, Analytical Chemistry 2020, 92, 3, 2756-2763
- Decibel P.Elpa, Gurpur Rakesh D.Prabhu, Shu-Pao Wu*, Kheng SooTay, Pawel L.Urban*, Automation of mass spectrometric detection of analytes and related workflows: A review, Talanta, 2020, 208, 120304
- Muthaiah Shellaiah, Turibius Simon, Natesan Thirumalaivasan, Kien Wen Sun*, Fu-Hsiang Ko, Shu-Pao Wu, Cysteamine-capped gold-copper nanoclusters for fluorometric determination and imaging of chromium(VI) and dopamine Microchimica Acta 2019, 186,788
- Ling-Fang Wei, Chong-Yan Chen, Chia-Kai Lai, Natesan Thirumalaivasan and Shu-Pao Wu*, A nano-molar fluorescent turn-on probe for copper(II) detection in living cells, Methods, 2019, 168, 18-23
- Natesan Thirumalaivasan, Parthiban Venkatesan, Ping-Shan Lai*,Shu-Pao Wu*, In Vitro and In Vivo Approach of Hydrogen-Sulfide-Responsive Drug Release Driven by Azide-Functionalized Mesoporous Silica Nanoparticles, ACS Applied Bio Materials 2019,2, 9, 3886-3896
- Chong-Guang Chen, Natarajan Vijay, Natesan Thirumalaivasan, Sivan Velmathi*, Shu-Pao Wu*, Coumarin-based Hg2+ fluorescent probe: Fluorescence turn-on detection for Hg2+ bioimaging in living cells and zebrafish, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 219, 135-140.
- Parthiban Venkatesan, Natesan Thirumalaivasan, Hsiu-Ping Yu, Ping-Shan Lai*, and Shu-Pao Wu*, Redox Stimuli Delivery Vehicle Based on Transferrin-Capped MSNPs for Targeted Drug Delivery in Cancer Therapy, ACS Applied Bio Materials 2019, 2, 4, 1623-1633
- Vijay Natarajan, Natesan Thirumalaivasan, Shu-Pao Wu and Velmathi Sivan*, A far-red to NIR emitting ultra-sensitive probe for the detection of endogenous HOCl in zebrafish and the RAW 264.7 cell line, Organic & Biomolecular Chemistry, 2019, 17, 3538-3544
- Chien-Wei Lu, Huan-Yi Hung, Hsin-Chen Sung, Yiong-Shing Sheu, Wen-Lung Lin and Shu-Pao Wu* , Total sulfur determination in petroleum fuels for routine quality control by sector field inductively coupled plasma mass spectrometry after dilution treatment, Journal of Analytical Atomic Spectrometry, 2019, 34, 570-576
- 84. Nithya Velusamy, Natesan Thirumalaivasan, Kondapa Naidu Bobba, Arup Podder, Shu-Pao Wu*, Sankarprasad, Bhuniya*, FRET-based dual channel fluorescent probe for detecting endogenous/exogenous H2O2/H2S formation through multicolor images, Journal of Photochemistry and Photobiology B: Biology, 2019, 191, 99-106
- Muthaiah Shellaiah, Turibius Simon, Parthiban Venkatesan, Kien Wen Sun*, Fu-Hsiang Ko, Shu-Pao Wu, Cysteamine-modified diamond nanoparticles applied in cellular imaging and Hg2+ ions detection, Applied Surface Science, 2019, 465, 340-350
- Yen-Yu Liu, Sanay Naha, Natesan Thirumalaivasan, Sivan Velmathi*, Shu-Pao Wu*, A novel nanomolar highly selective fluorescent probe for imaging mercury (II) in living cells and zebrafish, Sensors and Actuators B: Chemical, 2018, 277, 673-678
- Chien-Wei Lu, Huan-Yi Hung, Wen-Lung Lin, Shu-Pao Wu*, Analysis of metal ion impurity in tetraethyl orthosilicate by sector field inductively coupled plasma mass spectrometry, Spectrochimica Acta Part B: Atomic Spectroscopy, 2018, 149, 243-248
- Reguram Arumugaperumal,Parthiban Venkatesan,Tarun Shukla,Putikam Raghunath, Ravinder Singh, Shu-PaoWu, Ming-Chang Lin, Hong-Cheu Lin*, Multi-stimuli-responsive high contrast fluorescence molecular controls with a far-red emitting BODIPY-based [2]rotaxane, Sensors and Actuators B: Chemical, 2018, 270, 382-395.
- Ganesan Punithakumari1, Shu Pao Wu, Sivan Velmathi *, Highly Selective Detection of Cr3+ Ion with Colorimetric & Fluorescent Response Via Chemodosimetric Approach in Aqueous Medium, Journal of Fluorescence 2018, 28, 663–670
- Muthaiah Shellaiah, Turibius Simon, Parthiban Venkatesan, Kien Wen Sun*, Fu-Hsiang Ko, Shu-Pao Wu, Nanodiamonds conjugated to gold nanoparticles for colorimetric detection of clenbuterol and chromium(III) in urine, Microchimica Acta 2018, 185, 74
- Yu-Wei Tai, Yi-Chun Chiu, Po-Ting Wu, Jiashing Yu,* Yu-Cheng Chin, Shu-Pao Wu, Yu-Chun Chuang, Ho-Chen Hsieh, Ping-Shan Lai, Hsiu-Ping Yu, and Mei-Yi Liao*, Degradable NIR-PTT Nanoagents with a Potential Cu@Cu2O@Polymer Structure, ACS Appl. Mater. Interfaces 2018, 10, 5161−5174
- Nithya Velusamy, Natesan Thirumalaivasan, Kondapa Naidu Bobba, Shu-Pao Wu*, Sankarprasad Bhuniya*, A hydrogen sulfide triggered self-immolative fluorescent probe for lysosome labeling in live cells, New Journal of Chemistry, 2018, 42, 1590-1594
- Natarajan Vijay, Gopal Balamurugan, Parthiban Venkatesan, Shu Pao Wu and Sivan Velmath*, A triple action chemosensor for Cu2+ by chromogenic, Cr3+ by fluorogenic and CN− by relay recognition methods with bio-imaging of HeLa cells, Photochemical & Photobiological Science, 2017, 16, 1441–1448
- Chu-An Yang, Hsiu-Chuan Liu, Dong-Liang Lin, Ray H Liu, You-Zung Hsieh, Shu-Pao Wu*, Simultaneous Quantitation of Methamphetamine, Ketamine, Opiates and their Metabolites in Urine by SPE and LC–MS-MS. Journal of Analytical Toxicology, Volume 41, Issue 8, 1 October 2017, Pages 679–687
- Natesan Thirumalaivasan , Parthiban Venkatesan and Shu-Pao Wu*, Highly selective turn-on probe for H2S with imaging applications in vitro and in vivo, New Journal of Chemistry, 2017, 41, 13510-13515
- Tai-Hung Chen, Shu-Pao Wu*, Forensic applications of direct analysis in real time (DART) coupled to Q-orbitrap tandem mass spectrometry for the in situanalysis of pigments from paint evidence, Forensic Science International 2017, 277, 179-187
- Gopal Balamurugan, Sivan Velmathi, * Natesan Thirumalaivasan and Shu Pao Wu, New phenazine based AIE probes for selective detection of aluminium(III) ions in presence of other trivalent metal ions in living cells, Analyst, 2017, 142, 4721–4726
- Ling-Fang Wei, Natesan Thirumalaivasan, Yu-Cheng Liao, Shu-Pao Wu* Fluorescent coumarin-based probe for cysteine and homocysteine with live cell application, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2017, 183, 204-208.
- Parthiban Venkatesan, Natesan Thirumalivasan and Shu-Pao Wu*, A rhodamine-based chemosensor with diphenylselenium for highly selective fluorescence turn-on detection of Hg2+ in vitro and in vivo, RSC Advances, 2017, 7, 21733-21739
- Thangaraj Selvalakshmi, Parthiban Venkatesan, Shu-Pao Wu, S Velmathi, A. Chandra Bose, Gd2O3:RE3+ and GdAlO3:RE3+ (RE = Eu, Dy) Phosphor: Synthesis, Characterization and Bioimaging Application, Journal of Nanoscience and Nanotechnology, 2017, 17, 1178-1184
- Yu-Cheng Liao, Parthiban Venkatesan, Ling-Fang Wei, Shu-Pao Wu*, A coumarin-based fluorescent probe for thiols and its application in cell imaging, Sensors and Actuators B: Chemical, 2016, 232, 732–737.
- Tai-Hung Chen, Hsin-Yun Hsu, Shu-Pao Wu*, The detection of multiple illicit street drugs in liquid samples by direct analysis in real time (DART) coupled to Q-orbitrap tandem mass spectrometry, Forensic Science International, 2016, 267, 1-6.
- G. Pulido-Reyes, S. Das, F. Leganés, S. O. Silva, Shu-Pao Wu, W. Self, F. Fernández-Piñas, R. Rosal, S. Seal, Hypochlorite scavenging activity of cerium oxide nanoparticles, RSC Advances, 2016, 6, 62911-62915
- Srivardhan Reddy Gayam, Parthiban Venkatesan, Yi-Ming Sung, Shuo-Yuan Sung, Shang-Hsiu Hu, Hsin-Yun Hsu, Shu-Pao Wu*, An NAD(P)H: quinone oxidoreductase 1 (NQO1) enzyme responsive nanocarrier based on mesoporous silica nanoparticles for tumor targeted drug delivery in vitro and in vivo. Nanoscale, 2016, 8, 12307-12317.
- Hung-Cheng Lin, Sean Tsungyeh Yang, Sock Hoon Ng, Hsiao-Wen Zan*, Hsin-Fei Meng, Shi-Rong Liu, Chao-Yiu Chang, Shu-Pao Wu*, Gao-Fong Chang, Chen-Hsiung Hung, Hin Yong Wong, Hydro gel light-guiding conjunction for absorptive type multi-ions detection, Sensors and Actuators B: Chemical, 2016, 233, 535–539.
- Gopal Balamurugan, Parthiban Venkatesan, Shu Pao Wu, Sivan Velmathi*, Novel ratiometric turn-on fluorescent probe for selective sensing of cyanide ions, effect of substitution and bio-imaging studies, RSC Advances, 2016,6, 24229-24235.
- Yi-Ming Sung, Srivardhan Reddy Gayam, Pei-Ying Hsieh, Hsin-Yun Hsu, Eric Wei-Guang Diau and Shu-Pao Wu*, Quinone-Modified Mn-Doped ZnS Quantum Dots for Room-Temperature Phosphorescence Sensing of Human Cancer Cells That Overexpress NQO1, ACS Applied Materials & Interfaces, 2015, 7, 25961-25969.
- Shu-Hua Lo, Ming-Chun Wu, Shu-Pao Wu*, A turn-on fluorescent sensor for cysteine based on BODIPY functionalized Au nanoparticles and its application in living cell imaging, Sensors and Actuators B: Chemical, 2015, 221, 1366-1371.
- Sivalingam Suganya, Sivan Velmathi*, Parthiban Venkatesan, Shu-Pao Wu, Maria Susai Boobalan, A highly fluorescent zinc complex of a dipodal N-acyl hydrazone as a selective sensor for H2PO4− ions and application in living cells, Inorg. Chem. Front., 2015, 2, 649-656.
- Chih-Chia Huang *, Po-Yang Chang, Chien-Liang Liu, Jia-Pu Xu, Shu-Pao Wu and Wen-Chuan Kuo *, New insight on optical and magnetic Fe3O4 nanoclusters promising for near infrared theranostic applications, Nanoscale, 2015, 7, 12689-12697
- Wei-Chieh Chen, Parthiban Venkatesan and Shu-Pao Wu*, A turn-on fluorescent probe for hypochlorous acid based on HOCl-promoted removal of the C=N bond in BODIPY-hydrazone, New Journal of Chemistry, 2015, 39, 6892-6898.
- Shu-Hua Lo, Ming-Chun Wu, Parthiban Venkatesan, Shu-Pao Wu*, Colorimetric detection of Chromium (III) using O-phospho-L-serine dithiocarbamic acid functionalized gold nanoparticles, Sensors and Actuators B: Chemical, 2015, 220, 772-778.
- Chia-Jung Hsieh , Yu-Cheng Chen , Pei-Ying Hsieh , Shi-Rong Liu , Shu-Pao Wu ,You-Zung Hsieh , and Hsin-Yun Hsu, A Graphene Oxide-Based Nanocarrier Combined with a pH-Sensitive Tracer: a Vehicle for Concurrent pH Sensing and pH-Responsive Oligonucleotide Delivery. ACS Applied Materials & Interfaces, 2015,7, 11467–11475
- Wei-Chieh Chen, Parthiban Venkatesan, Shu-Pao Wu*, A highly selective turn-on fluorescent probe for hypochlorous acid based on hypochlorous acid–induced oxidative intramolecular cyclization of boron dipyrromethene-hydrazone, Analytica Chimica Acta, 2015, 882, 68-75
- Parthiban Venkatesan, Shu-Pao Wu*, A turn-on fluorescent pyrene-based chemosensor for Cu(II) with live cell application, RSC Advances, 2015, 5, 42591-42596.
- Shao-Lun Kao, Parthiban Venkatesan and Shu-Pao Wu* , A highly selective fluorescent sensor for Hg(II)based on an NTe2 chelating motif and its application to living cell imaging, New Journal of Chemistry, 2015, 39, 3551-3557.
- Shao-Lun Kao, Shu-Pao Wu*, A fluorescent turn-on probe for Hg(II) based on an NTe2 chelating motif and its application in living cell imaging, Sensors and Actuators B: Chemical, 2015, 212, 382-388.
- Duraisamy Udhayakumari, Sivan Velmathi*, Parthiban Venkatesan, Shu-Pao Wu, Anthracene coupled thiourea as a colorimetric sensor for F−/Cu2+and fluorescent sensor for Hg2+/picric acid, Journal of Luminescence, 2015, 161, 411-416.
- Duraisamy Udhayakumari, Sivan Velmathi*, Parthiban Venkatesan, Shu-Pao Wu, Heterocyclic ring based colorimetric and fluorescent chemosensor for transition metal ions in an aqueous medium, Journal of Luminescence, 2015, 158, 484-492.
- Parthiban Venkatesan, Shu-Pao Wu*, A turn-on fluorescent probe for hypochlorous acid based on the oxidation of diphenyl telluride, Analyst, 2015, 140, 1349-1355.
- Duraisamy Udhayakumari, Sivan Velmathi*, Parthiban Venkatesan and Shu-Pao Wu, A pyrene-linked thiourea as a chemosensor for cations and simple fluorescent sensor for picric acid, Analytical Methods, 2015, 7, 1161-1166.
- Jia-Rong Lin, Chien-Ju Chu, Parthiban Venkatesan, Shu-Pao Wu*, Zinc(II) and Pyrophosphate Selective Fluorescence Probe and its Application to Living Cell Imaging, Sensors and Actuators B: Chemical, 2015, 207, 563-570.
- Jiun-Ting Yeh, Parthiban Venkatesan, Shu-Pao Wu*, A highly selective turn-on fluorescent sensor for fluoride and its application in imaging of living cells, New Journal of Chemistry, 2014, 38, 6198-6204.
- Srivardhan Reddy Gayam, Shu–Pao Wu*, Redox Responsive Pd (II) Templated Rotaxane Nanovalve Capped Mesoporous Silica Nanoparticles: A Folic Acid Mediated Biocompatible Cancer-targeted Drug Delivery System. Journal of Materials Chemistry B, 2014, 2, 7009-7016.
- Shao-Lun Kao, Wan-Ying Lin, Parthiban Venkatesan, Shu-Pao Wu*, “Colorimetric detection of Cu(II): Cu(II)-induced deprotonation of NH responsible for color change”, Sensors and Actuators B: Chemical, 2014, 204, 688-693.
- Shi-Rong Liu, Chao-Yiu Chang, Shu-Pao Wu*, “A fluorescence turn-on probe for cysteine and homocysteine based on thiol-triggered benzothiazolidine ring formation“, Analytica Chimica Acta, 2014, 849, 64–69
- Duraisamy Udhayakumari, Sivan Velmathi*, Wei-Chieh Chen, Shu-Pao Wu, “ A Dual-mode Chemosensor: Highly Selective Colorimetric Fluorescent Probe for Cu2+ and F− ions”, Sensors and Actuators B: Chemical, 2014, 204, 375-381.
- Hao-Ming Liu, Parthiban Venkatesan, Shu-Pao Wu*, “A sensitive and selective fluorescent sensor for Zinc(II) and its application to living cell imaging”, Sensors and Actuators B: Chemical, 2014, 203, 719-725.
- Shiang-Yi Yu, Shu-Pao Wu*, “A highly selective turn-on fluorescence chemosensor for Hg(II) and its application in living cell imaging, Sensors and Actuators B: Chemical, 2014, 201, 25-30.
- Jiun-Ting Yeh, Wei-Chieh Chen, Shi-Rong Liu, Shu-Pao Wu*, “A coumarin-based sensitive and selective fluorescent sensor for copper(II) ions”, New Journal of Chemistry, 2014, 38, 4434-4439.
- I-Lin Lee, Yi-Ming Sung, Shu-Pao Wu*, “Triazole-acetate functionalized gold nanoparticles for colorimetric Pb(II) sensing”, RSC Advances, 2014, 4, 25251-25256.
- Yi-Ming Sung, Shu-Pao Wu*, “Colorimetric detection of Cd(II) ions based on di-(1H-pyrrol-2-yl)methanethione functionalized gold nanoparticles” , Sensors and Actuators B: Chemical, 2014, 201, 86-91.
- Duraisamy Udhayakumari, Sivan Velmathi*, Yi-Ming Sung, Shu-Pao Wu, “Highly fluorescent Probe for Copper (II) Ion based on Commercially Available compounds and Live Cell Imaging”, Sensors and Actuators B: Chemical, 2014, 198, 285–293
- Yi-Ming Sung, Shu-Pao Wu*, “Highly selective and sensitive colorimetric detection of Ag(I) using N-1-(2-mercaptoethyl)adenine functionalized gold nanoparticles”, Sensors and Actuators B: Chemical, 2014, 197, 172–176
- Shiang-Yi Yu, Chen-Yi Hsu, Wei-Chieh Chen, Ling-Fang Wei, Shu-Pao Wu*, “A hypochlorous acid turn-on fluorescent probe based on HOCl-promoted oxime oxidation and its application in cell imaging”, Sensors and Actuators B: Chemical, 2014, 196, 203-207.
- I-Lin Lee, Yi-Ming Sung, Chien-Hou Wu and Shu-Pao Wu* , “Colorimetric sensing of iodide based on triazole-acetamide functionalized gold nanoparticles, Microchimica Acta, 2014, 181, 573-579.
- Shi-Rong Liu, Mani Vedamalai and Shu-Pao Wu*, “Hypochlorous Acid Turn-on Boron Dipyrromethene Probe Based on Oxidation of Methyl Phenyl Sulfide”, Analytica Chimica Acta, 2013, 800, 71-76
- Yu-Ching Chen , I-Lin Lee, Yi-Ming Sung, and Shu-Pao Wu*, “Colorimetric detection of Al3+ ions using triazole-ether functionalized gold nanoparticles”, Talanta, 2013, 117, 70-74
- Yu-Ching Chen , I-Lin Lee, Yi-Ming Sung, and Shu-Pao Wu*, “Triazole functionalized Gold Nanoparticles for Colorimetric Cr3+ Sensing”, Sensors and Actuators B: Chemical, 2013, 188, 354-359
- Peter Kun Chung, Shi-Rong Liu, Hsuan-Fu Wang, Shu-Pao Wu*, “A Pyrene-based Highly Selective Turn-on Fluorescent Chemosensor for Iron(III) ions and its Application in Living Cell Imaging”, Journal of Fluorescence, 2013, 23, 1139-1145.
- Cho-Yen Chou, Shi-Rong Liu, Shu-Pao Wu*, “A highly selective turn-on fluorescent sensor for Cu(II) based on an NSe2 chelating moiety and its application in living cell imaging”, Analyst, 2013, 138, 3264-3270
- Yi-Ming Sung, Srivardhan Reddy Gayam, Shu-Pao Wu*, “The Oxidation of Phenylhydrazine by Tyrosinase”, Applied Biochemistry and Biotechnology, 2013, 169, 2420-2429
- Hsuan-Fu Wang, Shu-Pao Wu*,” A Pyrene-based Highly Selective Turn-On Fluorescent Sensor for Copper(II) Ions and Its Application in Living Cell Imaging”, Sensors and Actuators B: Chemical, 2013, 181, 743-748 24.
- Shi-Rong Liu and Shu-Pao Wu*, “Hypochlorous Acid Turn-on Fluorescent Probe Based on Oxidation of Diphenyl Selenide”, Organic Letters, 2013, 15, 878-881.
- Hsuan-Fu Wang, Shu-Pao Wu*, “Highly selective fluorescent sensors for mercury(II) ions and their applications in living cell imaging”, Tetrahedron, 2013, 69, 1965-1969.
- Shi-Rong Liu, Shu-Pao Wu*, “New Water-soluble Highly Selective Fluorescent Chemosensor for Fe(III) ions and Its Application to Living Cell Imaging”, Sensors and Actuators B: Chemical, 2012, 171– 172, 1110-1116.
- Mani Vedamalai, Shu-Pao Wu*, “A Bodipy-based Colorimetric and Fluorometric Chemosensor for Hg(II) Ions and its Application to Living Cell Imaging”, Organic & Biomolecular Chemistry, 2012, 10, 5410-5416.
- Mani Vedamalai, Shu-Pao Wu*, “A BODIPY-based Highly Selective Fluorescent Chemosensor for Hg2+ Ions and its Application to Living Cell Imaging”, European Journal of Organic Chemistry, 2012, 6, 1158-1163.
- Shu-Pao Wu*, Zhen-Ming Huang, Shi-Rong Liu, Peter Kun Chung, “ A Pyrene-based Highly Selective Turn-on Fluorescent Sensor for Copper(II) Ion and Its Application in Live Cell Imaging” Journal of Fluorescence, 2012, 22, 253-259.
- Shi-Rong Liu, Shu-Pao Wu*, “An NBD-based sensitive and selective fluorescent sensor for copper(II) ion” Journal of Fluorescence, 2011, 21, 1599-1605.
- Shu-Pao Wu, Marzia Bellei, Sheref S. Mansy, Gianantonio Battistuzzi, Marco Sola* and James A. Cowan* “Redox chemistry of the Schizosaccharomyces pombe ferredoxin electron-transfer domain and influence of Cys to Ser substitutions” Journal of Inorganic Biochemistry, 2011, 105, 806-811
- Shu-Pao Wu*, Yi-Pu Chen, Yi-Ming Sung “Colorimetric Detection of Fe3+ Ions Using Pyrophosphate Functionalized Gold Nanoparticles” Analyst, 2011, 136, 1887-1891.
- Shu-Pao Wu*, Tzu-Hao Wang, Shi-Rong Liu “A Highly Selective Turn-on Fluorescent Sensor for Copper(II) Ion.” Tetrahedron, 2010, 66, 9655-9658.
- Shu-Pao Wu*, Kun-Ju Du, Yi-Ming Sung, “Colorimetric Sensing of Cu(II): Cu(II) Induced Deprotonation of an Amide Responsible for Color Changes” Dalton Transactions, 2010, 39, 4363 – 4368.
- Marzia Bellei, Gianantonio Battistuzzi, Shu-Pao Wu, Sheref S. Mansy, James A. Cowan*, and Marco Sola*, “Control of reduction thermodynamics in [2Fe-2S] ferredoxins. Entropy-enthalpy compensation and the influence of surface mutations”. Journal of Inorganic Biochemistry, 2010, 104, 691-696
- Stephen R.Wecksler; Stefan Stoll; Ha Tran; Olafur T. Magnusson; Shu-Pao Wu; David King; R. David Britt; Judith P. Klinman*, “Pyrroloquinoline Quinone Biogenesis: Demonstration that PqqE from Klebsiella pneumoniae is a Radical SAM Enzyme.” Biochemistry, 2009, 48, 10151–10161.
- Shu-Pao Wu*, Shi-Rong Liu, “A new water-soluble fluorescent Cu(II) chemosensor based on tetrapeptide histidyl-glycyl-glycyl-glycine (HGGG).” Sensors and Actuators B: Chemical, 2009, 141, 187-191
- Shu-Pao Wu*, Ray-Yui Huang, Kun-Ju Du, “Colorimetric sensing of Cu(II) by 2-methyl-3-[(pyridin-2-ylmethyl)-amino]-1,4-naphthoquinone: Cu(II) induced deprotonation of NH responsible for color changes.” Dalton Transactions, 2009, 4735-4740.
- Shu-Pao Wu* and Chih-Hao Lee, “Infinite Chiral Single-helical Structures Formed by the Self-assembly of Cu(II)-N-(2-pyridylmethyl)-aspartate Complexes.” CrystEngComm, 2009, 11, 219-222.
- Shu-Pao Wu, and J. A. Cowan*, “Iron-Sulfur Cluster Stability. Kinetics and Mechanism of Ligand-Promoted Cluster Degradation.” Chem. Commun. 2007, 82-84.
- Shu-Pao Wu, Sheref S. Mansy, and J. A. Cowan*, “Iron-Sulfur Cluster Biosynthesis. Molecular Chaperone DnaK Promotes Stability of the [2Fe-2S] Center of Thermotoga maritima IscU and Inhibit Cluster Transfer Activity”. Biochemistry, 2005, 44, 4284-4293.
- Sheref S. Mansy, Shu-Pao Wu, and J. A. Cowan*, “Iron-Sulfur Cluster Biosynthesis. Biochemical Characterization of the Conformational Dynamics of Thermotoga maritima IscU and the Relevance for Cellular Cluster Assembly”. J. Biol. Chem. 2004, 279, 10469-10475.
- Shu-Pao Wu, and J. A. Cowan* “Iron-Sulfur Cluster Biosynthesis. Kinetic Analysis of [2Fe-2S] Cluster Transfer from holo ISA to apo Fd”. Biochemistry 2003, 42, 5784-5791.
- Shu-Pao Wu, Gong Wu, Kristene K. Surerus, and J. A. Cowan* “Iron-sulfur cluster biosynthesis. Kinetic analysis of [2Fe-2S] cluster transfer from holo ISU to apo Fd: role of redox chemistry and a conserved aspartate”. Biochemistry 2002, 41, 8876-85.
- Gong Wu, Sheref S. Mansy, Shu-Pao Wu, Kristene K. Surerus, Matthew W. Foster, J. A. Cowan*, “Characterization of an Iron-Sulfur Cluster Assembly Protein (ISU1) from Schizosaccharomyces pombe”. Biochemistry 2002, 41, 5024-5032.
- Chan-Cheng Su*, Tsai-Yun Tai, Shu-Pao Wu, Sue-Lein Wang, Fen-Lin Liao, “Spectroscopic and electronic properties of mixed ligand aminoacidatocopper(II) complexes. Molecular structure of [Cu(4,7-dimethyl-1,10-phenanthroline) (L-phenylalaninato)](ClO4).” Polyhedron 1999, 18, 2361-2368.
- Chan-Cheng Su*, Shu-Pao Wu, Chiou-Yuh Wu, Tsung-Yi Chang, “Electronic and bonding properties of acetylacetonato copper(II) complexes. Molecular structure of [Cu(acetylacetonato)(1,10-phenanthroline) (ClO4) (0.5CH3CN)].” Polyhedron 1995, 14, 267-275.
Invited Speech
- 2016 The 5th International Conference on Molecular Sensors and Molecular Logic Gates (MSMLG2016), July 24-28, 2016, Bath, United Kingdom. Oral presentation topic ” Quinone Modified Mn-Doped ZnS Quantum Dots For The Room Temperature Phosphorescence Sensing Of Human Cancer Cells That Overexpress NQO1”
- 2016 The International Symposium, The 67th Divisional Meeting on Colloid and Interface Chemistry Japan (Colloid Asahikawa) September 22 -24, Asahikawa, Hokkaido, Japan. Oral presentation topic “Design and Synthesis of Enzyme Responsive Nanocarriers based on Mesoporous Silica Nanoparticles for Targeted drug Delivery Applications”
- 2017 2nd Asian Conference on Chemosensors & Imaging Probes (Asian-ChIP 2017) ICCAS Beijing, October 23 -26, 2017. Oral presentation topic “Design and Synthesis of Enzyme Responsive Nanocarriers based on Mesoporous Silica Nanoparticles for Targeted drug Delivery Applications”
- 2017 4th Japan-Taiwan-Singapore-Hong Kong Quadrilateral Symposium, Hong Kong, December 10-12, 2017. Oral presentation topic “Design and Synthesis of Enzyme Responsive Nanocarriers based on Mesoporous Silica Nanoparticles for Targeted Drug Delivery Applications.
- 2018 9th Asian Biological Inorganic Chemistry Conference, Singapore, December 9-14. Oral presentation topic “Design and Synthesis of Enzyme Responsive Nanocarriers based on Mesoporous Silica Nanoparticles for Targeted drug Delivery Applications”.
- 2019 3rd Asian Conference on Chemosensors & Imaging Probes (Asian-ChIP 2019) Amritsar, India, November 06-09, 2019. Oral presentation topic “An In Vitro and In Vivo Approach of Hydrogen Sulfide-Responsive Drug Release Driven by Azide-Functionalized Mesoporous Silica Nanoparticles”.
Research Highlights
Our research efforts combine inorganic chemistry with biochemical tools in an interdisciplinary approach to study metal ion homeostasis and design biomaterials for clinic use. Topics of current interest include:
1.Metal ion sensor 2. Biosensors 3. MSNPs drug delivery
