電話
03-5712121 ext 56501
吳宜霖 Yi-Lin Wu
副教授
- 電話 03-5712121 #56575
- 傳真
- 辦公室 科學二館 R517
- Email: yilin.wu@nycu.edu.tw
- 實驗室電話 03-5712121 #56553
學歷
2008-2012蘇黎世聯邦理工學院化學及應用生物科學系博士
2007-2008蘇黎世聯邦理工學院化學及應用生物科學系碩士
2002-2005國立台灣大學化學系學士
經歷
國立陽明交通大學應用化學系副教授 (2025/08–present)
英國卡地夫大學化學院高級講師 (2024/08–2025/07)
英國卡地夫大學化學院講師 (2019/01–2024/07 )
美國西北大學研究副教授 (2017/05–2018/11 )
美國西北大學研究助理教授 (2014/01~2017/12 )
美國西北大學博士後研究員 (2012/05~2013/12 )
Associate Professor, National Yang Ming Chiao Tung University (2025/08–present)
Senior Lecturer in Materials Chemistry, Cardiff University (2024/08–2025/07)
Lecturer in Materials Chemistry, Cardiff University (2019/01–2024/07)
Research Associate Professor, Northwestern University (2017/05–2018/11)
Research Assistant Professor, Northwestern University (2014/05–2017/12)
Postdoctoral Associate, Northwestern University (2012/05–2013/12)
學術榮譽
- 2025 Yushan Young Fellow
- 2022 Fellow of the Higher Education Academy (FHEA)
- 2013 Postdoctoral Professional Development Travel Award
- 2012–2013 Swiss National Science Foundation (SNF) Fellowship for Prospective Researches
- 2009–2011 Scholarship Fund of the Swiss Chemical Industry (SSCI)
- 2008 Novartis M.Sc. Fellowship
- 2007–2008 Scholarship from the Funds Prof. Fritz Medicus, ETH Zürich
- 2003–2005 President’s Award, National Taiwan University
- 2005 Dean’s Award of College of Science, National Taiwan University
- 2004 Microelectronics Corporation (UMC) Scholarship
著作
Publications
- Huang, Y.; Wu, C.; Lu, A.; Wang, J.; Liang, J.; Sun, H.; Yang, L.; Duan, S.; Berezin, A. A.; Wu, C.; Zhang, B.; Wu, Y.-L.; Tsai, Y.-H. “A Single Bioorthogonal Reaction for Multiplex Cell Surface Protein Labeling” J. Am. Chem. Soc. 2025, 147, 1612–1623.
- Chen, J; Dai, G.; Duan, S.; Huang, Y.; Wu, Y.-L.; Xie, Z.; Tsai, Y.-H. “Selective Protein Degradation through Tetrazine Ligation of Genetically Incorporated Unnatural Amino Acids” Chem. Asian J. 2024, 19, e202400824.
- Williams, T. L.; Taily, I. M.; Hatton, L.; Berezin, A. A.; Wu, Y.-L.; Moliner, V.; Świderek, K.; Tsai, Y.-H.; Luk, L. Y. P. “Secondary Amine Catalysis in Enzyme Design: Broadening Protein Template Diversity through Genetic Code Expansion” Angew. Chem. Int. Ed. 2024, 63, e202403098.
- Wu, Y.-Y.; Wu, Y.-L.; Lin, C.-L.; Chen, H.-C.; Chuang, Y.-Y.; Chen, C.-H.; Chou, C.-M. “Butterfly-Shaped Dibenz[a,j]anthracenes: Synthesis and Photophysical Properties” Org. Lett. 2023, 25, 7763–7768.
- Wright, A. I.; Kariuki, B. M.; Wu, Y.-L. “Synthesis, Solid-state Structure, and Electrochemical Properties of Thienodipyrimidine-2,4,5,7-tetra(thi)ones” Arkivoc 2023, 202311998.
* Dedicated to Professor Tien-Yau Luh on the occasion of his 76th birthday. - Wu, Y.-L.; Wright, A. I. “Why Does Thionating a Carbonyl Molecule Make It a Better Electron Acceptor?” Phys. Chem. Chem. Phys. 2023, 25, 1342–1348.
- Zhou, L.; He, R.; Qin, Y.; Wu, Y.-L.; Jiang, L.; Zhou, D.-D.; Zhang, L. “Multiple C–H⋯Anion and N–H⋯Anion Hydrogen Bond Directed Two-Dimensional Crystalline Nanosheets with Precise Distance Control of Surface Charges for Enhanced DNA Capture” Soft Matter. 2021, 17, 9125–9130.
- Wright, A. I.; Kariuki, B. M.; Wu, Y.-L. “Triplet-Forming Thionated Donor-Acceptor Chromophores for Electrochemically Amphoteric Photosensitization” Eur. J. Org. Chem. 2021, 4647–4652.
* This article also appears in François Diederich Tribute. - Zhou, J.; Stojanović, L.; Berezin, A. A.; Battisti, T.; Gill, A.; Kariuki, B. M.; Bonifazi, D.; Crespo-Otero, R.; Wasielewski, M. R.; Wu, Y.-L. “Organic Room-temperature Phosphorescence from Halogen-bonded Organic Frameworks: Hidden Electronic Effects in Rigidified Chromophores” Chem. Sci. 2021, 12, 767–773.
- del Prado, A.; González-Rodríguez, D.; Wu, Y.-L. “Functional Systems Derived from Nucleobase Self-assembly” ChemistryOpen 2020, 9, 409–430.
* Top Cited Article 2020–2021. - Galstyan, A; Maurya, Y. K.; Zhylitskaya, H.; Bae, Y.; J.; Wu, Y.-L.; Wasielewski, M. R.; Lis, T.; Dobrindt, U; Stępień, M. “π-Extended Donor–Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation” Chem. Eur. J. 2020, 26, 8262–8266.
- Bae, Y. J.; Christensen, J. A.; Kang, G.; Malliakas, C. D.; Zhou, J.; Nelson, J. N.; Young, R. M.; Wu, Y.-L.; Van Duyne, R. P.; Schatz, G. C.; Wasielewski, M. R. “Design Principles for Efficient Singlet Fission in Anthracene-Based Organic Semiconductors” SPIE 11084, Physical Chemistry of Semiconductor Materials and Interfaces XVIII, 2019, DOI: 10.1117/12.2527346.
- Bae, Y. J.; Krzyaniak, M. D.; Majewski, M. B.; Desroches, M.; Morin, J. F.; Wu, Y.-L.; Wasielewski, M. R. “Competition between Singlet Fission and Spin-Orbit-Induced Intersystem Crossing in Anthanthrene and Anthanthrone Derivatives” ChemPlusChem 2019, 84, 1432–1438.
- Phelan, B. T.; Zhang, J.; Huang, G. J.; Wu, Y.-L.; Zarea, M.; Young, R. M.; Wasielewski, M. R. “Quantum Coherence Enhances Electron Transfer Rates to Two Equivalent Electron Acceptors” J. Am. Chem. Soc. 2019, 141, 12236–12239.
- Bae, Y. J.; Christensen, J. A.; Kang, G.; Zhou, J.; Young, R. M.; Wu, Y.-L.; Van Duyne, R. P.; Schatz, G. C.; Wasielewski, M. R. “Substituent Effects on Energetics and Crystal Morphology Modulate Singlet Fission in 9,10-Bis(Phenylethynyl)Anthracenes” J. Chem. Phys. 2019, 151, 044501.
- Mandal, A.; Schultz, J. D.; Wu, Y.-L.; Coleman, A. F.; Young, R. M.; Wasielewski, M. R. “Transient Two-Dimensional Electronic Spectroscopy: Coherent Dynamics at Arbitrary Times Along the Reaction Coordinate” J. Phys. Chem. Lett. 2019, 10, 3509–3515.
- Bae, Y. J.; Kang, G.; Malliakas, C. D.; Nelson, J. N.; Zhou, J.; Young, R. M.; Wu, Y.-L.; Van Duyne, R. P.; Schatz, G. C.; Wasielewski, M. R. “Singlet Fission in 9,10-Bis(Phenylethynyl)Anthracene Thin Films” J. Am. Chem. Soc. 2018, 140, 15140–15144.
- Gregolinska, H.; Majewski, M.; Chmielewski, P. J.; Gregolinski, J.; Chien, A.; Zhou, J.; Wu, Y.-L.; Bae, Y. J.; Wasielewski, M. R.; Zimmerman, P. M.; Stepien, M. “Fully Conjugated [4]Chrysaorene. Redox-Coupled Anion Binding in a Tetraradicaloid Macrocycle” J. Am. Chem. Soc. 2018, 140, 14474–14480.
- Wu, Y.-L.; Bobbitt, N. S.; Logsdon, J. L.; Powers-Riggs, N. E.; Nelson, J. N.; Liu, X.; Wang, T. C.; Snurr, R. Q.; Hupp, J. T.; Farha, O. K.; Hersam, M. C.; Wasielewski, M. R. “Tunable Crystallinity and Charge Transfer in 2-Dimensional G-Quadruplex Organic Frameworks” Angew. Chem. Int. Ed. 2018, 57, 3985–3989.
- Goswami, S.; Nelson, J. N.; Islamoglu, ; Wu, Y.-L.; Farha, O. K.; Wasielewski, M. R. “Photoexcited Naphthalene Diimide Radical Anion Linking the Nodes of a Metal–Organic Framework: A Heterogeneous Super-reductant” Chem. Mater. 2018, 30, 2488–2492.
- Mauck, C. M.; Bae Y. J.; Chen, M.; Powers-Riggs, N. E.; Wu, Y.-L.; Wasielewski, M. R. “Charge Transfer Character in a Covalent Diketopyrrolopyrrole Dimer: Implications for Singlet Fission” ChemPhotoChem 2018, 2, 223–233.
- Brown, K. E.; Singh, A. P. N.; Wu, Y.-L.; Ma, L.; Mishra, A. K.; Phelan, B. T.; Young, R. M.; Lewis, F. D.; Wasielewski, M. R. “Fluorescent Excimers and Exciplexes of the Purine Base Derivative 8-Phenylethynylguanine in DNA Hairpins” Faraday Discuss. 2017, 207, 217–232.
- Margulies, E. A.; Kerisit, N.; Gawel, P.; Mauck, C. M.; Ma, L.; Miller, C. E.; Young, R. M.; Trapp, N.; Wu, Y.-L.; Diederich, F.; Wasielewski, M. R. “Substituent Effects on Singlet Exciton Fission in Polycrystalline Thin Films of Cyano-Substituted Diaryltetracenes” J. Phys. Chem. C 2017, 121, 21262–21271.
- Brown, K. E.; Singh, A. P. N.; Wu, Y.-L.; Mishra, A. K.; Zhou, J.; Lewis, F. D.; Young, R. M.; Wasielewski, M. R. “Tracking Hole Transport in DNA Hairpins Using a Phenylethynylguanine Nucleobase” J. Am. Chem. Soc. 2017, 139, 12084–12092.
- Mauck, C. M.; Hartnett, P. E.; Wu, Y.-L.; Miller, C. E.; Marks, T. J.; Wasielewski, M. R. “Singlet Fission within Diketopyrrolopyrrole Nanoparticles in Water” Chem. Mater. 2017, 26, 6810–6817.
- Goswami, S.; Miller, C. E.; Logsdon, J. L.; Buru, C. T.; Wu, Y.-L.; Bowman, D. N.; Islamoglu, T.; Asiri, A. M.; Cramer, C. J.; Wasielewski, M. R.; Hupp, J. T.; Farha, O. K. “Atomistic Approach toward Selective Photocatalytic Oxidation of a Mustard-Gas Simulant: A Case Study with Heavy-Chalcogen-Containing PCN-57 Analogues” ACS Appl. Mater. Interfaces 2017, 9, 19535–19540.
- Šolomek, T.; Powers-Riggs, N. E.; Wu, Y.-L.; Young, R. M.; Krzyaniak, M. D.; Horwitz, N. E.; Wasielewski, M. R. “Electron Hopping and Charge Separation within a Naphthalene-1,4:5,8-bis(dicarboximide) Chiral Covalent Organic Cage” J. Am. Chem. Soc. 2017, 139, 3348–3351.
- Mazza, M. M. A.; Yamazaki, S.; Mai, D. X.; Padgaonkar, S.; Peurifoy, S.; Goncalves, A.; Wu, Y.-L.; Hu, Q.; Scott; A. M. “Photoinduced Charge Recombination in Dipolar D-A-A Photonic Liquid Crystal Polymorphs” Phys. Chem. Chem. Phys. 2017, 19, 4588–4596.
- Wu, Y.-L.; Horwitz, N. E.; Chen, K.-S.; Gomez-Gualdron, D. A.; Luu, N. S.; Ma, L.; Wang, T. C.; Hersam, M. C.; Hupp, J. T.; Farha, O. K.; Snurr, R. Q; Wasielewski, M. R. “G-quadruplex Organic Frameworks” Nat. Chem. 2017, 9, 466–472.
- Hartnett, P. E.; Mauck, C. M.; Harris, M. A.; Young, R. M.; Wu, Y.-L.; Marks, T. J.; Wasielewski, M. R. “Influence of Anion Delocalization on Electron Transfer in a Covalent Porphyrin Donor–Perylenediimide Dimer Acceptor System” J. Am. Chem. Soc. 2017, 139, 749–756.
- Hartnett, P. E.; Margulies, E. A.; Mauck, C. M.; Miller, S. A.; Wu, Y.; Wu, Y.-L.; Marks, T. J.; Wasielewski, M. R. “Effects of Crystal Morphology on Singlet Exciton Fission in Diketopyrrolopyrrole Thin Films” J. Phys. Chem. B. 2016, 120, 1357–1366.
- Huang, G.-J.; Harris, M. A.; Krzyaniak, M. D.; Margulies, E. A.; Dyar, S. M.; Lindquist, R. J.; Wu, Y.; Roznyatovskiy, V. V.; Wu, Y.-L.; Young, R. M.; Wasielewski, M. R. “Photoinduced Charge and Energy Transfer Within meta– and para-Linked Chlorophyll a–Perylene-3,4:9,10-bis(dicarboximide) Donor-Acceptor Dyads” J. Phys. Chem. B. 2016, 120, 756–765.
- Margulies, E. A.; Wu, Y. L.; Gawel, P.; Miller, S. A.; Shoer, L. E.; Schaller, R. D.; Diederich, F.; Wasielewski, M. R. “Sub-Picosecond Singlet Exciton Fission in Cyano-Substituted Diaryltetracenes” Angew. Chem. Int. Ed. 2015, 54, 8679–8683.
- Wu, Y.; Shi, R.; Wu, Y.-L.; Holcroft, J. M.; Liu, Z.; Frasconi, M.; Wasielewski, E. R.; Li, H.; Stoddart, J. F. “Complexation of Polyoxometalates with Cyclodextrins” J. Am. Chem. Soc. 2015, 137, 4111–4118.
- Gawel, P.; Wu, Y.-L.; Finke, A. D.; Trapp, N.; Zalibera, M.; Boudon, C.; Gisselbrecht, J.-P.; Schweizer, W. B.; Gescheidt, G.; Diederich, F. “Push–Pull Buta-1,2,3-trienes: Exceptionally Low Rotational Barriers of Cumulenic C=C Bonds and Their Proacetylenic Reactivity” Chem. Eur. J. 2015, 21, 6215–6225.
- Wu, Y.-L.; Brown K. E.; Gardner, D. M.; Dyar, S. M.; Wasielewski, M. R. “Photoinduced Hole Injection into a Self-assembled π-Extended G-quadruplex” J. Am. Chem. Soc. 2015, 137, 3981–3990.
* Highlighted in JACS Spotlights: J. Am. Chem. Soc. 2015, 137, 3995. - Lefler, K. M.; Kim, C. H.; Wu, Y.-L.; Wasielewski, M. R. “Self-assembly of supramolecular light-harvesting arrays from symmetric perylene-3,4-dicarboximide trefoils” J. Phys. Chem. Lett. 2014, 5, 1608–1615.
- Wu, Y.-L.; Brown, K. E.; Wasielewski, M. R. “Extending Photoinduced Charge Separation Lifetimes by Using Supramolecular Design: Guanine–Perylenediimide G-quadruplex” J. Am. Chem. Soc. 2013, 135, 13322–13325.
* Highlighted in JACS Spotlights: J. Am. Chem. Soc. 2013, 135, 13611. - Wu, Y.-L.; Stuparu, M. C.; Boudon, C.; Gisselbrecht, J.-P.; Schweizer, W. B.; Baldridge, K.; Siegel, J. S.; Diederich, F. “Structural, Optical, and Electrochemical Properties of Three-dimensional Push–Pull Corannulenic Chormophores” J. Org. Chem. 2012, 77, 11014–11026.
- Wu, Y.-L.; Ferroni, F.; Pieraccini, S.; Schweizer, W. B.; Frank, B. B.; Spada G. P.; Diederich F. “1,2-Di(phenylethynyl)ethenes with Axially Chiral, 2,2′-Bridged 1,1′-Binaphthyl Substituents: Potent Cholesteric Liquid-Crystal Inducers” Org. Biomol. Chem. 2012, 10, 8016–8026.
- Wu, Y.-L.; Tancini, F.; Schweizer, W. B.; Paunescu, D.; Boudon, C.; Gisselbrecht, J.-P.; Jarowski, P. D.; Dalcanale, E.; Diederich, F. “Proacetylenic Reactivity of a Push–Pull Buta-1,2,3-triene: New Chromophores and Supramolecular Systems” Chem. Asian J. 2012, 7, 1185–1190.
- Tancini, F.; Wu, Y.-L.; Schweizer, W. B.; Gisselbrecht, J.-P.; Boudon, C.; Jarowski, P. D.; Beels, M. T.; Biaggio, I.; Diederich, F. “1,1-Dicyano-4-[4-(diethylamino)phenyl]buta-1,3-dienes: Structure–Property Relationships.” J. Org. Chem. 2012, 2756–2765.
- Breiten, B.; Wu, Y.-L.; Jarowski, P. D.; Gisselbrecht, J.-P.; Boudon, C.; Griesser, M.; Onitsh, C.; Gescheidt, G.; Schweizer, W. B.; Langer, N.; Lennartz, C; Diederich F. “Donor-substituted Octacyano[4]dendralenes: a New Class of Cyano-rich Nonplanar Organic Acceptors” Chem. Sci. 2011, 2, 88–93.
- Wu, Y.-L.; Bureš, F.; Jarowski, P. D.; Schweizer, W. B.; Gisselbrecht, J.-P.; Boudon, C.; Diederich F. “Proaromaticity: Organic Charge-transfer Chromophores with Small HOMO–LUMO Gaps” Chem. Eur. J. 2010, 16, 9592–9605.
* Highlighted in Synfacts 2010, 1242. - Šišak, D.; McCusker, L. B.; Buckl, A.; Wuitschik, G.; Wu, Y.-L.; Schweizer, W. B.; Dunitz, J. D. “The Search for Tricyanomethane (Cyanoform)” Chem. Eur. J. 2010, 16, 7224–7230.
*Referenced in the article of cyanoform in Wikipedia: http://en.wikipedia.org/wiki/Cyanoform - Wu, Y.-L.; Jarowski, P. D.; Schweizer, W. B.; Diederich F. “Mechanistic Investigation of the Dipolar [2+2] Cycloaddition-cycloreversion Reaction Between 4-(N,N-Dimethylamino)phenylacetylene and Arylated 1,1-Dicyanovinyl Derivatives to Form Intramolecular Charge-transfer Chromophores” Chem. Eur. J. 2010, 16, 202–211.
- Lin, H.-C.; Hsu, J.-H.; Lee, C.-K.; Tai, O. Y.-H.; Wang, C.-H.; Chou, C.-M.; Chen, K.-Y.; Wu, Y.-L.; Luh, T.-Y. “Observing Second-order Nonlinear Optical Properties by Symmetry Breaking in Centrosymmetric Furan-containing Oligoaryl Cyclophandienes” Chem. Eur. J. 2009, 15, 13201–13209.
- Chou, C.-M.; Biju, A. T.; Wang, H.-W.; Wu, Y.-L.; Zhang, G.-F.; Chen, C.-H.; Yang, K.-W.; Lim, T.-S.; Lee, S.-L.; Huang, M.-J.; Chen, C.-h.; Tsai, P.-Y.; Lin, K.-C.; Huang, S.-L.; Luh, T.-Y. “Polymeric Ladderphanes” J. Am. Chem. Soc. 2009, 131, 12579–12858.
- Jarowski, P. D.; Wu, Y.-L.; Boudon, C.; Gisselbrecht, J.-P.; Gross, M.; Schweizer, W. B.; Diederich F. “New Donor–Acceptor Chromophores by Formal [2+2] Cycloaddition of Donor-substituted Alkynes to Dicyanovinyl Derivatives” Org. Biomol. Chem. 2009, 7, 1312–1322.
- Jarowski, P. D.; Wu, Y.-L.; Schweizer, W. B.; Diederich F. “1,2,3-Triazoles as Conjugative π-Linkers in Push–Pull Chromophores: Importance of Substituent Positioning on Intramolecular Charge-transfer” Org. Lett. 2008, 10, 3347–3350.
- Lin, C.-L.; Wu, Y.-L.; Chen, C.-L.; Chou, C.-M.; Luh, T.-Y. “Sequential Electrochemical Oxidation of Alternating Benzene-furan Oligomers” J. Org. Chem. 2007, 72, 8531–853.
